Hypochlorous Acid as a Potential Wound Care Agent. Part II. Stabilized Hypochlorous Acid: Its Role in Decreasing Tissue Bacterial Bioburden and Overcoming the Inhibition of Infection on Wound Healing
Source
Frank, Ko et al. Hypochlorous Acid as a Potential Wound Care Agent. Part II. Stabilized Hypochlorous Acid: Its Role in Decreasing Tissue Bacterial Bioburden and Overcoming the Inhibition of Infection on Wound Healing. Journal of burns and wounds.
Date 2007
Abstract
This study examined the use of NVC-101, a stabilized form of hypochlorous acid, as a topical antimicrobial for chronic wounds. It was tested on a rodent model with infected wounds to see if it could reduce bacteria without harming the healing process. NVC-101 at 0.01% (100ppm) concentration and a pH of 3.5 to 4.0 showed effectiveness, especially when applied for short periods (15-30 minutes). Although it was not as powerful as silver sulfadiazine in killing bacteria, NVC-101 helped wounds heal better. The study suggests NVC-101 could be a useful treatment for wounds if its pH is maintained correctly in clinical use.